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Since unilateral T-RDN and bilateral A-RDN had comparable effects on GLP-1 mediated hemodynamic changes, it is possible that unilateral interruption of renal afferent input (limited input) to the central nervous system is sufficient to reduce sympathetic outflow affecting GLP-1 mediated hemodynamic changes

The capsule format protects the peptide from premature degradation and allows for precise dosing without measuring or drawing doses as required with injectable formulations